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Journal of Cosmetic and Laser Therapy
Volume 18, 2016 - Issue 6
Min Seok Kim,Ji Yun Jung,Eun Byul Cho,Eun Joo Park,Kwang Ho Kim &Kwang Joong Kim
Pages 317-322 | Received 09 Aug 2015, Accepted 19 Feb 2016, Accepted author version posted online: 24 Mar 2016, Published online: 22 Apr 2016
Introduction: Severe onychomycosis in the elderly is a common condition and generally difficult to treat. Long-pulsed Nd:YAG (LPNY) laser has been found to be useful in the treatment of onychomycosis. We sought to evaluate the effectiveness of 1,064-nm LPNY laser in the treatment of severe onychomycosis.
Materials and methods: Forty nails in 13 patients with severe onychomycosis were divided into two groups. Each group received eight treatment sessions at one-week intervals with 1,064-nm LPNY laser. Parameters for group A were 0.3 ms pulse duration, 5 mm spot size, 16 J/cm2 fluence, and 10 Hz frequency, and those for group B were 0.6 ms, 2 mm, 225 J/cm2, and 5 Hz. Clinical and mycological clearance were evaluated at 12 and 24 weeks after initial treatment.
Results: Clinical improvements at 12 and 24 weeks presented 47.6 and 57.1% in group A, and 26.3 and 36.8% in group B. In the treated nails with clinical improvement, mycological positive rates at 24 weeks were approximately 40% in both groups.
Discussion: The treatment of onychomycosis using 1,064-nm LPNY laser were incomplete in clinical and mycological improvement, and it could imply a lot of potential recurrence. We suggest that 1,064-nm LPNY laser for severe onychomycosis should need additional or combined therapy with other therapeutic options.
